STA-based MutectorTM Reagents
MutectorTM (Mutation Detector) reagents have been developed and optimized for the STA technology to detect somatic mutations in oncology and identify genetic variations in Pharmacogenetics. Our MutectorTM reagents have following unique features:
- Accessible platform - run on industry standard PCR instrument and ABI Genetic Analyzer
- Color and size detection - enable easy analysis and clear identification of mutation detection peak(s)
- Multiplexing capability - amplify multiple mutations from different loci, genes, alleles, exons, and introns in a single tube
- Excellent sensitivity – detect up to 1% mutation contribution in a background of wild type genomic DNA from analytical samples
- Built-in internal control - ensure at least one peak, either wild type or mutant will be present in each sample
- Simple protocol – get clear, easy-to-read results in less than 4 hours
- Universal – core reagents can be used for different gene mutation and genotyping
Available Product
Oncology Mutation Detection
| Cat. No. | Product Name | Targeted Mutations | Size | Documents |
| GP02-EK | BRAF mutation detection kit | 5 BRAF mutations in codon V600 | 32 rxn | Manual |
| EP12 | BRAF mutation detection kit | Real time PCR detection of V600E | 32 rxn | Manual |
| GP05-C3 | KRAS mutation detection kit | 12 KRAS mutations in codon 12 & 13 | 32 rxn | Manual, Product flyer |
| GP06 | KRAS mutation detection kit | 5 KRAS mutations in codon 61 | 32 rxn | Manual, Product flyer |
| GP08 | PIK3CA Mutation detection kit | 5 PIK3CA mutation in exon 6 & 9 | 32 rxn | Manual |
| GP18 | NRAS mutation detection kit | 12 NRAS mutations in codon 12 & 13 | 32 rxn | Manual, Product flyer |
| GP19 | NRAS mutation detection kit | 4 NRAS mutations in codon 61 | 32 rxn | Manual, Product flyer |
| Cor-A | MutectorTM Core Reagents A | Universal reagents for detection of point mutations | 32 rxn | Product Flyer |
MutectorTM Core Reagents C | Universal reagents for detection of deletion, insertion, and translocations | 32 rxn |
Pharmacogenetics Genotyping
| Cat. No. | Product Name | Targeted SNPs | Size | Documents |
| GP03 | Warfarin genotyping kit | VKORC1 -1639G>A, CYP2C9 *2, *3 | 32 rxn | Manual |
| GP11 | CYP2D6 genotyping kit | CYP2D6 *2, *3, *4, *5, *6, *9, *10, *17, *41, 4180G>C | 32 rxn | Manual, Product flyer |
| GP12 | CYP2C19 genotyping kit | CYP2C19 *2, *3, *4, *5, *6, *7, *8, *17 | 32 rxn | Manual, Product flyer |
For research use only. Not for use in diagnostic procedures.
