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Test Service
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Highly sensitive assays to identify mutations associated with the EGFR pathway
KRAS panel (12 mutations)
B-raf panel (3 mutations)
PIK3CA panel (5 mutations) |
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FDA 510(k) approved |
eQ-PCR LC Warfarin Genotyping kit recently received approval from US Food and Drug Administration.
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Paraffin (FFPE) sample
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FFPE DNA Extraction Kit
Highly efficient DNA extraction in two simple steps. The WaxFreeTM DNA kit is designed for:
Paraffin-embedded samples (FFPE)
Fine needle aspiration (FNA)
Fresh/frozen tissues
Cells
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Successfully extract DNA from 10 year-old FFPE sample. Click image below
DNA extracted from one section (1 cm2 ) is sufficient for up to 100 PCR reactions. |
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Detect DNA Mutations that Affect Individual Drug Response
Identifying mutations in the EGFR signaling pathway is crucial because these mutations result in resistance to anti-EGFR drug response.
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Important gene mutations in EGFR pathway:
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12 mutations in KRAS
Codon V600 mutations in B-raf
6 mutations in PIK3CA
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TrimGen's MutectorTM technology is able to accurately identify each mutation. |
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Two assay platforms:
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Sequencer platform
Microplate platform |
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| Clear-cut results of the Mutector Assay (KRAS):
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| | Mutation detection kits for EGFR pathway are available:
| | KRAS |
| BRAF |
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PIK3CA |
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Mutector technology has been used in many clinical studies. see publications
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