Detect DNA Mutations that Affect Individual Drug Response
Identifying mutations in the EGFR signaling pathway is crucial because these mutations result in resistance to anti-EGFR drug response.
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Important gene mutations in EGFR pathway:
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12 mutations in KRAS
Codon V600 mutations in B-raf
5 mutations in PIK3CA
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TrimGen's MutectorTM technology is able to accurately identify each mutation. |
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Two assay platforms:
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Sequencer platform
Microplate platform |
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Clear-cut results of the Mutector II Assay (KRAS):
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| Mutation detection kits for EGFR pathway are available:
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| KRAS |
| BRAF |
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PIK3CA |
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Mutector technology has been used in many clinical studies. see publications
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