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KRAS mutation kits
Enrich the mutation signal 20-fold and
detect 12 mutations in codons 12 & 13

Mutation Detection
  Colorimetric mutation detection
  Multiplex mutation detection

Infectious Pathogen Detection
  Virus
  Bacteria

Reagents for Paraffin sample (FFPE)
  Paraffin sample DNA extraction
  Paraffin sample RNA extraction
  Paraffin-PCR combo kit

PCR Clean-up
  Spin cloumn (large sample volume)
  TF Filter tips (small sample volume)

Buccal DNA Collection for Genetic Test
  Buccal cell collection
  Buccal DNA extraction

Test Services

Publications
 
 
Diagnostic value of pyrosequencing for the BRAFV600E mutation in ultrasound-guided fine-needle aspiration biopsy samples of thyroid incidentalomas
Clinical Endocrinology, 2008

Pyrophosphorolysis Detects B-RAF Mutations in Primary Uveal Melanoma
Investigative Ophthalmology and Visual Science. 2008;49:23-27.

Clinical implications of BRAF mutation in thyroid carcinoma.
Trends in Endocrinology & Metabolism 19, (4) May-June 2008, Pages 138-145

RNA mutations of prox1 detected in human esophageal cancer cells by the shifted termination assay
Biochemical and Biophysical Research Communications 359 (2) 258-262, 2007

Distribution of BRAF T1799A(V600E) Mutations Across Various Types of Benign Nevi: Implications for Melanocytic Tumorigenesis.
American Journal of Dermatopathology. 29(6):534-537, December 2007

BRAF Mutations in Melanocytic Lesions and Papillary Thyroid Carcinoma Samples Identified Using Melting Curve Analysis of Polymerase Chain Reaction Products.
Archives of Pathology and Laboratory Medicine 131:1361–1367, 2007

Fine-Needle Aspiration Molecular Analysis for the Diagnosis of Papillary Thyroid Carcinoma Through BRAFV600E Mutation and RET/PTC Rearrangement
Thyroid. November 1, 2007, 17(11): 1109-1115

BRAF mutation analysis in fine needle aspiration (FNA) cytology of the thyroid.
Diagn Mol Pathol. 2006 Sep;15(3):136-43.

Vitamin D and survival from melanoma.
Melanoma Research. 16 Supplement 1:S26-S27, September 2006.

High Frequency of BRAFV600E Mutation in Acquired Nevi and Small Congenital Nevi, but Low Frequency of Mutation in Medium-Sized Congenital Nevi.
Journal of Investigative Dermatology (2006) 126, 2111–2118

Mutational status of B-RAF and N-RAS in fresh melanomas.
Melanoma Research. 16 Supplement 1:S27, September 2006

Statistical survey of deaths from malignant melanoma in Japan, 1955-2004.
Melanoma Research. 16 Supplement 1:S27, September 2006.

MUTATIONAL STATUS OF B-RAF AND NRAS IN FRESH MELANOMAS: PP083.
Pigment Cell Research. 19(5):542-543, October 2006.

Vitamin D and survival from melanoma.
Melanoma Research. 16 Supplement 1:S26-S27, September 2006.

T1799A BRAF Mutations in Conjunctival Melanocytic Lesions.
Investigative Ophthalmology and Visual Science. 2005;46:3027-3030

Genetic prediction of autoimmunity: Initial oligogenic prediction of anti-islet autoimmunity amongst DR3/DR4–DQ8 relatives of patients with type 1A diabetes.
Journal of Autoimmunity Volume 25, Supplement 1, 2005, Pages 40-45

T1799A BRAF mutations in conjunctival melanocytic lesions. Invest Ophthalmol Vis Sci. 2005 Sep;46(9):3027-30.

Mutational activation of BRAF is not a major event in sporadic childhood papillary thyroid carcinoma. Mod Pathol. 2005 Jul;18(7):898-902.

Colorimetric approach to high-throughput mutation analysis. BioTechniques 2005 April; 38:635-639

A new technology for mutation detection. Ann N Y Acad Sci. 2004 Jun;1022:257-62.

BRAF mutations in anaplastic thyroid carcinoma: implications for tumor origin, diagnosis and treatment. Mod Pathol. 2004 Nov;17(11):1359-63.

Detection of BRAF Mutation on Fine Needle Aspiration Biopsy Specimens: A New Diagnostic Tool for Papillary Thyroid Cancer. J Clin Endocrinol Metab, June 2004, 89(6):2867-2872

The V599E BRAF mutation is uncommon in biliary tract cancers. Mod Pathol. 2004 Nov;17(11):1386-91.

Exon 15 BRAF mutations are uncommon in melanomas arising in nonsun-exposed sites. Clin Cancer Res. 2004 May 15;10(10):3444-7.

Mutational Analysis of BRAF in Fine Needle Aspiration Biopsies of the Thyroid: A Potential Application for the Preoperative Assessment of Thyroid Nodules. Vol. 10, 2761-2765, April 15, 2004

Absence of V599E BRAF mutations in desmoplastic melanomas
Cancer. Volume 103, Issue 4; Pages 788-792

Hypermethylation of CpG island loci of multiple tumor suppressor genes in retinoblastoma.
Experimental Eye Research, Volume 86, Issue 2; Pages 201-206 Y.

BRAF Mutation Predicts a Poorer Clinical Prognosis for Papillary Thyroid Cancer
The Journal of Clinical Endocrinology & Metabolism Vol. 90, No. 12, Pages 6373-6379

Quantitative Assessment of Promoter Methylation Profiles in Thyroid Neoplasms
The Journal of Clinical Endocrinology & Metabolism Vol. 90, No. 7, Pages 4011-4018

Applications of molecular techniques to fine-needle aspiration biopsy
Cancer Cytopathology Volume 111 Issue 2, Pages 106-122.

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