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Highly sensitive assays to identify mutations associated with the EGFR pathway

EGFR panel (28 mutations)

KRAS panel (12 mutations)

B-raf panel (3 mutations)

PIK3CA panel (5 mutations)

FDA 510(k) approved

eQ-PCR LC Warfarin Genotyping kit recently received approval from US Food and Drug Administration.

Paraffin (FFPE) sample

FFPE DNA Extraction Kit
Highly efficient DNA extraction in two simple steps. The WaxFree^TM DNA kit is designed for:

Paraffin-embedded samples (FFPE)

Fine needle aspiration (FNA)

Fresh/frozen tissues

Cells

Successfully extract DNA from 10 year-old FFPE sample. Click image below

DNA extracted from one section (1 cm² ) is sufficient for up to 100 PCR reactions.

Detect DNA Mutations that Affect Individual Drug Response

Identifying mutations in the EGFR signaling pathway is crucial because these mutations result in resistance to anti-EGFR drug response.

Important gene mutations in EGFR pathway:

12 mutations in KRAS

Codon V600 mutations in B-raf

5 mutations in PIK3CA

TrimGen's Mutector^TM technology is able to accurately identify each mutation.

Two assay platforms:

Sequencer platform
Microplate platform

Clear-cut results of the Mutector Assay (KRAS):