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News Release

July 11, 2008 - Sparks, Maryland

TrimGen scientists respond to the demand for KRAS testing

For many years colo-rectal cancer treatment was standard and consistent. The EGFR pathway was targeted by various drugs such as Panitumumab^TM and Cetuximab^TM to treat patients diagnosed with colon cancer. Unfortunately, many of these patients developed cancer via another pathway, the KRAS proto-oncogene, and did not respond to traditional drug therapy. Thus the need for genetic screening prior to treatment arose.

TrimGen has reengineered the KRAS mutation panel to now screen for all mutations on codons 12 and 13 respectively. With 1-2% sensitivity, the Mutector II KRAS panel is unrivaled in effectiveness, ease-of-use and accuracy. We are pleased to unveil the new Mutector II assay and continue to support the changing field of oncology research.

Time Line

2008

May
TrimGen presents a poster introducting a highly sensitive eQ-PCR^TM (enhanced Q-PCR) technology at the ASM, June 2-6, annual meeting in Boston. More than 250 clinical cerebrospinal fluid samples (CSF) samples were used for the clinical validation and results are discussed.

April
TrimGen and Spartan BioScience join forces and present eQ-PCR^TM viral detection technology at the 24th Clinical Virology Symposium in Daytona Beach, FL April 27 - 30. Learn more

TrimGen featured in Science Magazine

March
BuccalQuick^TM 2.0 is released! The new kit builds upon the previous platform of BuccalQuick^TM DNA extraction and further simplifies the protocol. DNA from buccal cells can now be extracted at room temperature in five minutes using TrimGen technology.

February
TrimGen is proud to annouce the launch of DNA Quick^TM. A new line of DNA preparation products for mouse tail, ear punch and culture cells.

January
New test product lines, screening and quantification assay for Leukemia/Lymphoma launched.
FusionArray
FusionCount

2007

November
A single tube test for detection and differentiation of Herpes simplex virus (type 1 & 2) and Enterovirus (HSV/EnV) is developed and the assay has been validated by over 250 clinical samples.

Warfarin genotyping reagents (single tube test in Mutector II platform) now available.

October
TrimGen completed a clinical trial for its LightCycler Warfarin genotyping kit and submitted an application to the FDA for510K approval. Learn more

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